Side effects of CDK4/6 inhibitors in the treatment of HR+/HER2? advanced breast cancer: a systematic review and meta-analysis of randomized controlled trials
نویسندگان
چکیده
Background: Although combination of cyclin-dependent kinase 4 and 6(CDK4/6) inhibitors with endocrine therapy for advanced breast cancer (ABC) prolongs PFS in patients, but also has associated toxic side effects. However, few previous studies have summarized the effects CDK4/6 inhibitors. Therefore, this study corresponding CDK/6 inhibitors, which is great importance doctors patients to understand how balance high survival rate brought by drugs decreased quality life improve management BC.
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ژورنال
عنوان ژورنال: Annals of palliative medicine
سال: 2021
ISSN: ['2224-5839', '2224-5820']
DOI: https://doi.org/10.21037/apm-21-1096